Sweet Syndrome: A Rare but Important Skin Condition

Sweet syndrome, also known as acute febrile neutrophilic dermatosis, is a rare inflammatory skin disorder characterized by the sudden onset of painful red skin lesions, fever, and increased white blood cells (neutrophils).

The condition often appears abruptly and may affect the face, neck, arms, or upper body. While uncommon, it is clinically important because it can be linked to infections, autoimmune diseases, certain cancers, or reactions to medications.

Key Symptoms

• Painful red plaques or nodules

• Fever

• Fatigue

• Elevated white blood cell count

Diagnosis is confirmed through clinical evaluation and a skin biopsy showing dense neutrophilic inflammation without vasculitis.

Causes and Triggers

Sweet syndrome may be triggered by:

• Recent infections

• Autoimmune disorders

• Blood-related cancers

• Certain medications

Drug-induced cases usually improve after stopping the triggering medication.

Treatment

Systemic corticosteroids are the first-line treatment and typically lead to rapid improvement within days. Early diagnosis helps prevent complications and ensures better outcomes.

Medical Disclaimer

This content is for informational purposes only and does not replace professional medical advice.